Analogy of Drug Target in cartoon

My analogy of cat’s face with drug target such as HIV-protease. What makes them look like a cat? Conserved features (ears and whiskers), and Differential features (eyes and the shape of the face)

Screenshot (4)

Drug is an inhibitor that stop the cat from meowing, such as this Star Corps Trooper helmet.

Screenshot (5)

Let’s see what are possibilities if we are to fit cat’s face with a Star Corps Clone Trooper Helmet

Screenshot (6)

 

Screenshot (7)

Bad target arises when Tom’s picture is in complex because Jerry is there and it is of low resolution

Screenshot (8)

Fluff friend cat called Syri and Garfield looks so common. The colour are the same and they have no special features, and they are promiscuous. If we have enough amount of pictures and they are in the same pose without distortion, it help with the design.

Screenshot (9)

To discriminate them for helmet design, we need to understand their special features. If they are too similar, we may misidentify closely related cats such as the two kitties from Sanrio. It shows the reason why something we are targeting can fit the same models (this may cause drug’s side effects in the case of kinases)

Screenshot (10)

Felix and Sylvester are unique. They are easy for the design of specific helmets for masking them.Screenshot (11)Most of the effort is CRISPR-cas9 is devoted to find a smart synthetic cat or a helmet that can perform our goal to control these mask singers.

 

 

 

Advertisements